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Spatiotemporal control of necroptotic cell death and plasma membrane recruitment using engineered MLKL domains

Necroptosis is a form of programmed necrotic cell death in which a signaling cascade induces oligomerization of mixed lineage kinase domain-like (MLKL) protein, leading to plasma membrane rupture. Necroptotic cell death is recognized as important for protection against viral infection and has roles...

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Detalles Bibliográficos
Autores principales: Taslimi, Amir, Fields, Kaiah M., Dahl, Kristin D., Liu, Qi, Tucker, Chandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709077/
https://www.ncbi.nlm.nih.gov/pubmed/36446770
http://dx.doi.org/10.1038/s41420-022-01258-0

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