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The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression

Transient receptor potential channel TRPM2 is highly expressed in many cancers and involved in regulation of key physiological processes including mitochondrial function, bioenergetics, and oxidative stress. In Stage 4 non-MYCN amplified neuroblastoma patients, high TRPM2 expression is associated wi...

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Detalles Bibliográficos
Autores principales: Bao, Lei, Festa, Fernanda, Hirschler-Laszkiewicz, Iwona, Keefer, Kerry, Wang, Hong-Gang, Cheung, Joseph Y., Miller, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709080/
https://www.ncbi.nlm.nih.gov/pubmed/36446940
http://dx.doi.org/10.1038/s41598-022-25138-w