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Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans

Alternations of redox metabolism have been associated with the extension of lifespan in roundworm Caenorhabditis elegans, caused by moderate mitochondrial dysfunction, although the underlying signalling cascades are largely unknown. Previously, we identified transcriptional factor Krüppel-like facto...

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Detalles Bibliográficos
Autores principales: Hermeling, Johannes CW, Herholz, Marija, Baumann, Linda, Cores, Estela Cepeda, Zečić, Aleksandra, Hoppe, Thorsten, Riemer, Jan, Trifunovic, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709155/
https://www.ncbi.nlm.nih.gov/pubmed/36442394
http://dx.doi.org/10.1016/j.redox.2022.102533