Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma

Allogeneic natural killer (NK) cell adoptive transfer is a promising treatment for several cancers but is less effective for the treatment of multiple myeloma. In this study, we report on quadruple gene-engineered induced pluripotent stem cell (iPSC)-derived NK cells designed for mass production fro...

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Detalles Bibliográficos
Autores principales: Cichocki, Frank, Bjordahl, Ryan, Goodridge, Jodie P., Mahmood, Sajid, Gaidarova, Svetlana, Abujarour, Ramzey, Davis, Zachary B., Merino, Aimee, Tuininga, Katie, Wang, Hongbo, Kumar, Akhilesh, Groff, Brian, Witty, Alec, Bonello, Greg, Huffman, Janel, Dailey, Thomas, Lee, Tom T., Malmberg, Karl-Johan, Walcheck, Bruce, Höpken, Uta, Rehm, Armin, Valamehr, Bahram, Miller, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709157/
https://www.ncbi.nlm.nih.gov/pubmed/36446823
http://dx.doi.org/10.1038/s41467-022-35127-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709157/
https://www.ncbi.nlm.nih.gov/pubmed/36446823
http://dx.doi.org/10.1038/s41467-022-35127-2

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