Cargando…

Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma

Sodium iodide symporter (NIS) gene transfer for active accumulation of iodide in tumor cells is a powerful theranostic strategy facilitating both diagnostic and therapeutic application of radioiodide. In glioblastoma (GBM), the blood-brain barrier (BBB) presents an additional delivery barrier for nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Spellerberg, Rebekka, Benli-Hoppe, Teoman, Kitzberger, Carolin, Hageneier, Mara, Schwenk, Nathalie, Öztürk, Özgür, Steiger, Katja, Multhoff, Gabriele, Eiber, Matthias, Schilling, Franz, Weber, Wolfgang A., Kälin, Roland E., Glass, Rainer, Nelson, Peter J., Wagner, Ernst, Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709165/
https://www.ncbi.nlm.nih.gov/pubmed/36458201
http://dx.doi.org/10.1016/j.omto.2022.10.013