Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH

11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Although 11βHSD1 has been implicated in numerous metabolic syndromes, such as obesity and diabetes, the functional roles of 11βHSD1 during pr...

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Detalles Bibliográficos
Autores principales: Lee, Su-Yeon, Kim, Sanghwa, Choi, Inhee, Song, Yeonhwa, Kim, Namjeong, Ryu, Hyung Chul, Lim, Jee Woong, Kang, Hyo Jin, Kim, Jason, Seo, Haeng Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709168/
https://www.ncbi.nlm.nih.gov/pubmed/36446766
http://dx.doi.org/10.1038/s41419-022-05452-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709168/
https://www.ncbi.nlm.nih.gov/pubmed/36446766
http://dx.doi.org/10.1038/s41419-022-05452-x

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