Cargando…
Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH
11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Although 11βHSD1 has been implicated in numerous metabolic syndromes, such as obesity and diabetes, the functional roles of 11βHSD1 during pr...
Autores principales: | Lee, Su-Yeon, Kim, Sanghwa, Choi, Inhee, Song, Yeonhwa, Kim, Namjeong, Ryu, Hyung Chul, Lim, Jee Woong, Kang, Hyo Jin, Kim, Jason, Seo, Haeng Ran |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709168/ https://www.ncbi.nlm.nih.gov/pubmed/36446766 http://dx.doi.org/10.1038/s41419-022-05452-x |
Ejemplares similares
-
HO-1089 and HO-1197, Novel Herbal Formulas, Have Antitumor Effects via Suppression of PLK1 (Polo-like Kinase 1) Expression in Hepatocellular Carcinoma
por: Song, Yeonhwa, et al.
Publicado: (2023) -
Chromenopyrimidinone Controls Stemness and Malignancy by suppressing CD133 Expression in Hepatocellular Carcinoma
por: Song, Yeonhwa, et al.
Publicado: (2020) -
Expression of HYOU1 via Reciprocal Crosstalk between NSCLC Cells and HUVECs Control Cancer Progression and Chemoresistance in Tumor Spheroids
por: Lee, Minji, et al.
Publicado: (2021) -
11β-hydroxysteroid dehydrogenase-1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis
por: Xiao, Wei, et al.
Publicado: (2020) -
Molecular characterization of bovine placental and ovarian 20α-hydroxysteroid dehydrogenase
por: Naidansuren, Purevjargal, et al.
Publicado: (2011)