Cargando…

Mechanistic insights into poly(C)-binding protein hnRNP K resolving i-motif DNA secondary structures

I-motifs are four-strand noncanonical secondary structures formed by cytosine (C)-rich sequences in living cells. The structural dynamics of i-motifs play essential roles in many cellular processes, such as telomerase inhibition, DNA replication, and transcriptional regulation. In cells, the structu...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Wen-Qiang, Zhang, Xin, Bai, Di, Shan, Song-Wang, Guo, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709238/
https://www.ncbi.nlm.nih.gov/pubmed/36334628
http://dx.doi.org/10.1016/j.jbc.2022.102670