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Mechanistic insights into poly(C)-binding protein hnRNP K resolving i-motif DNA secondary structures
I-motifs are four-strand noncanonical secondary structures formed by cytosine (C)-rich sequences in living cells. The structural dynamics of i-motifs play essential roles in many cellular processes, such as telomerase inhibition, DNA replication, and transcriptional regulation. In cells, the structu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709238/ https://www.ncbi.nlm.nih.gov/pubmed/36334628 http://dx.doi.org/10.1016/j.jbc.2022.102670 |