The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity

Alpha-1,6-fucosyltransferase (FUT8) synthesizes core fucose in N-glycans, which plays critical roles in various physiological processes. FUT8, as with many other glycosyltransferases, is a type-II membrane protein, and its large C-terminal catalytic domain is linked to the FUT8 stem region, which co...

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Detalles Bibliográficos
Autores principales: Tomida, Seita, Nagae, Masamichi, Kizuka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709245/
https://www.ncbi.nlm.nih.gov/pubmed/36336076
http://dx.doi.org/10.1016/j.jbc.2022.102676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709245/
https://www.ncbi.nlm.nih.gov/pubmed/36336076
http://dx.doi.org/10.1016/j.jbc.2022.102676

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