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Pharmacological basis of bergapten in gastrointestinal diseases focusing on H(+)/K(+) ATPase and voltage-gated calcium channel inhibition: A toxicological evaluation on vital organs

Aim and objectives: This study aimed to establish a pharmacological basis for evaluating the effects of bergapten (5-methoxypsoralen) in gastrointestinal diseases and assessment of its toxicological profile. Methods: The pharmacokinetic profile was evaluated using the SwissADME tool. AUTODOCK and Py...

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Detalles Bibliográficos
Autores principales: Aslam, Huma, Khan, Arif-ullah, Qazi, Neelum Gul, Ali, Fawad, Hassan, Syed Shams ul, Bungau, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709249/
https://www.ncbi.nlm.nih.gov/pubmed/36467058
http://dx.doi.org/10.3389/fphar.2022.1005154