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Pigment epithelium-derived factor is an interleukin-6 antagonist in the RPE: Insight of structure-function relationships

Retinal and choroidal inflammatory lesions increase the levels of the pro-inflammatory cytokine interleukin-6 (IL-6). Pigment epithelium-derived factor (PEDF) has anti-inflammatory properties, but it is not known if it can prevent the production of IL-6 by the retinal pigment epithelium. To investig...

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Detalles Bibliográficos
Autores principales: Bernardo-Colón, Alexandra, Lerner, Miriam, Becerra, S. Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709256/
https://www.ncbi.nlm.nih.gov/pubmed/36467689
http://dx.doi.org/10.3389/fphys.2022.1045613