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A state-of-the-art review of tamoxifen as a potential therapeutic for duchenne muscular dystrophy

Introduction: This systematic review analyzes the state-of-art repurposing of the drug tamoxifen (TAM) in the treatment of Duchenne Muscular Dystrophy (DMD), including its mechanism of action, toxicological findings, and past and ongoing clinical trials. A parallel aim of this work was to explore wh...

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Detalles Bibliográficos
Autores principales: Botti, Valeria, Menzel, Olivier, Staedler, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709317/
https://www.ncbi.nlm.nih.gov/pubmed/36467064
http://dx.doi.org/10.3389/fphar.2022.1030785