Modeling study of long-term stability of the monoclonal antibody infliximab and biosimilars using liquid-chromatography–tandem mass spectrometry and size-exclusion chromatography–multi-angle light scattering

Monoclonal antibodies (mAbs) represent a dynamic class of biopharmaceutical products, as evidenced by an increasing number of market authorizations for mAb innovator and biosimilar products. Stability studies are commonly performed during product development, for instance, to exclude unstable molecu...

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Detalles Bibliográficos
Autores principales: Legrand, Pauline, Dufaÿ, Sophie, Mignet, Nathalie, Houzé, Pascal, Gahoual, Rabah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709354/
https://www.ncbi.nlm.nih.gov/pubmed/36449030
http://dx.doi.org/10.1007/s00216-022-04396-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709354/
https://www.ncbi.nlm.nih.gov/pubmed/36449030
http://dx.doi.org/10.1007/s00216-022-04396-7

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