Peptidylarginine deiminase 4 deficiency in bone marrow cells prevents plaque progression without decreasing atherogenic inflammation in apolipoprotein E-knockout mice

INTRODUCTION: Despite multiple studies in the past, the role of peptidylarginine deiminase 4 (PAD4) in atherosclerosis is currently insufficiently understood. In this regard, PAD4 deletion or inhibition of enzymatic activity was previously reported to ameliorate disease progression and inflammation....

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Detalles Bibliográficos
Autores principales: Paunel-Görgülü, Adnana, Conforti, Andreas, Mierau, Natalia, Zierden, Mario, Xiong, Xiaolin, Wahlers, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709396/
https://www.ncbi.nlm.nih.gov/pubmed/36465436
http://dx.doi.org/10.3389/fcvm.2022.1046273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709396/
https://www.ncbi.nlm.nih.gov/pubmed/36465436
http://dx.doi.org/10.3389/fcvm.2022.1046273

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