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How important is the N-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids?
N-α-acetylation is a frequently occurring post-translational modification in eukaryotic proteins. It has manifold physiological consequences on the regulation and function of several proteins, with emerging studies suggesting that it is a global regulator of stress responses. For decades, in vitro b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709446/ https://www.ncbi.nlm.nih.gov/pubmed/36466161 http://dx.doi.org/10.3389/fnins.2022.1003997 |