Discovery of novel thioquinazoline-N-aryl-acetamide/N-arylacetohydrazide hybrids as anti-SARS-CoV-2 agents: Synthesis, in vitro biological evaluation, and molecular docking studies

In the current investigation, two novel series of (tetrahydro)thioquinazoline-N-arylacetamides and (tetrahydro)thioquinazoline-N-arylacetohydrazides were designed, synthesized and investigated for their antiviral activity against SARS-CoV-2. The thioquinazoline-N-arylacetamide 17g as well as the tet...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdel-Mohsen, Heba T., Omar, Mohamed A., Kutkat, Omnia, Kerdawy, Ahmed M. El, Osman, Alaa A., GabAllah, Mohamed, Mostafa, Ahmed, Ali, Mohamed A., Diwani, Hoda I. El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709698/
https://www.ncbi.nlm.nih.gov/pubmed/36465802
http://dx.doi.org/10.1016/j.molstruc.2022.134690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709698/
https://www.ncbi.nlm.nih.gov/pubmed/36465802
http://dx.doi.org/10.1016/j.molstruc.2022.134690

Ejemplares similares