Lysine-targeting inhibition of amyloid β oligomerization by a green perilla-derived metastable chalcone in vitro and in vivo

Oligomers of amyloid β (Aβ) represent an early aggregative form that causes neurotoxicity in the pathogenesis of Alzheimer's disease (AD). Thus, preventing Aβ aggregation is important for preventing AD. Despite intensive studies on dietary compounds with anti-aggregation properties, some identi...

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Detalles Bibliográficos
Autores principales: Murakami, Kazuma, Sakaguchi, Yoshiki, Taniwa, Kota, Izuo, Naotaka, Hanaki, Mizuho, Kawase, Taiji, Hirose, Kenji, Shimizu, Takahiko, Irie, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709778/
https://www.ncbi.nlm.nih.gov/pubmed/36544574
http://dx.doi.org/10.1039/d2cb00194b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709778/
https://www.ncbi.nlm.nih.gov/pubmed/36544574
http://dx.doi.org/10.1039/d2cb00194b

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