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Chemical proteomic analysis of bile acid-protein targets in Enterococcus faecium

Bile acids are important gut microbiota metabolites that regulate both host and microbial functions. To identify the direct protein targets of bile acids in Enterococcus, we synthesized and validated the activity of a lithocholic acid (LCA) photoaffinity reporter, x-alk-LCA-3. Chemical proteomics of...

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Detalles Bibliográficos
Autores principales: Yang, Xinglin, Zhao, Xiaohui, Chen, Victor, Hang, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709779/
https://www.ncbi.nlm.nih.gov/pubmed/36544573
http://dx.doi.org/10.1039/d2cb00178k