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Evolution of the SARS-CoV-2 mutational spectrum

SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here we examine whether this mutational process itself has changed during viral evolution. To do this, we quantify the relative rates of different types of single nucleotide mutations at four-fold degenerate sites in the viral gen...

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Detalles Bibliográficos
Autores principales: Bloom, Jesse D, Beichman, Annabel C, Neher, Richard A, Harris, Kelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709787/
https://www.ncbi.nlm.nih.gov/pubmed/36451887
http://dx.doi.org/10.1101/2022.11.19.517207