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SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual

The milder clinical manifestations of Omicron infection relative to pre-Omicron SARS CoV-2 raises the possibility that extensive evolution results in reduced pathogenicity. To test this hypothesis, we quantified induction of cell fusion and cell death in SARS CoV-2 evolved from ancestral virus durin...

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Detalles Bibliográficos
Autores principales: Lustig, Gila, Ganga, Yashica, Rodel, Hylton, Tegally, Houriiyah, Jackson, Laurelle, Cele, Sandile, Khan, Khadija, Jule, Zesuliwe, Reedoy, Kajal, Karim, Farina, Bernstein, Mallory, Moosa, Mahomed-Yunus S., Archary, Derseree, de Oliveira, Tulio, Lessells, Richard, Abdool Karim, Salim S., Sigal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709797/
https://www.ncbi.nlm.nih.gov/pubmed/36451879
http://dx.doi.org/10.1101/2022.11.23.22282673