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SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual
The milder clinical manifestations of Omicron infection relative to pre-Omicron SARS CoV-2 raises the possibility that extensive evolution results in reduced pathogenicity. To test this hypothesis, we quantified induction of cell fusion and cell death in SARS CoV-2 evolved from ancestral virus durin...
Autores principales: | Lustig, Gila, Ganga, Yashica, Rodel, Hylton, Tegally, Houriiyah, Jackson, Laurelle, Cele, Sandile, Khan, Khadija, Jule, Zesuliwe, Reedoy, Kajal, Karim, Farina, Bernstein, Mallory, Moosa, Mahomed-Yunus S., Archary, Derseree, de Oliveira, Tulio, Lessells, Richard, Abdool Karim, Salim S., Sigal, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709797/ https://www.ncbi.nlm.nih.gov/pubmed/36451879 http://dx.doi.org/10.1101/2022.11.23.22282673 |
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