Spatiotemporal Self-Assembly of Peptide Amphiphiles by Carbonic Anhydrase IX-Targeting Induces Cancer-Lysosomal Membrane Disruption

[Image: see text] To achieve spatiotemporal control, an enzyme-instructed self-assembly system is widely used, but this approach typically has a small effect on cellular fate. In this study, we show that the intralysosomal assembly by a carbonic anhydrase IX (CAIX)-targeting peptide amphiphile (Pep-...

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Detalles Bibliográficos
Autores principales: Kim, Dohyun, Kim, Sangpil, Park, Gaeun, Choi, Huyeon, Ryu, Ja-Hyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709935/
https://www.ncbi.nlm.nih.gov/pubmed/36465549
http://dx.doi.org/10.1021/jacsau.2c00422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709935/
https://www.ncbi.nlm.nih.gov/pubmed/36465549
http://dx.doi.org/10.1021/jacsau.2c00422

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