Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease

[Image: see text] Metal ions, such as copper and zinc ions, have been shown to strongly modulate the self-assembly of the amyloid-β (Aβ) peptide into insoluble fibrils, and elevated concentrations of metal ions have been found in amyloid plaques of Alzheimer’s patients. Among the physiological trans...

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Detalles Bibliográficos
Autores principales: Abelein, Axel, Ciofi-Baffoni, Simone, Mörman, Cecilia, Kumar, Rakesh, Giachetti, Andrea, Piccioli, Mario, Biverstål, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709942/
https://www.ncbi.nlm.nih.gov/pubmed/36465548
http://dx.doi.org/10.1021/jacsau.2c00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709942/
https://www.ncbi.nlm.nih.gov/pubmed/36465548
http://dx.doi.org/10.1021/jacsau.2c00438

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