[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity

[Image: see text] Helicenes are high interest synthetic targets with unique conjugated helical structures that have found important technological applications. Despite this interest, helicenes have had limited impact in chemical biology. Herein, we disclose a first-in-class antimitotic helicene, hel...

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Detalles Bibliográficos
Autores principales: Rushworth, James L., Thawani, Aditya R., Fajardo-Ruiz, Elena, Meiring, Joyce C. M., Heise, Constanze, White, Andrew J. P., Akhmanova, Anna, Brandt, Jochen R., Thorn-Seshold, Oliver, Fuchter, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709948/
https://www.ncbi.nlm.nih.gov/pubmed/36465552
http://dx.doi.org/10.1021/jacsau.2c00435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709948/
https://www.ncbi.nlm.nih.gov/pubmed/36465552
http://dx.doi.org/10.1021/jacsau.2c00435

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