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[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity
[Image: see text] Helicenes are high interest synthetic targets with unique conjugated helical structures that have found important technological applications. Despite this interest, helicenes have had limited impact in chemical biology. Herein, we disclose a first-in-class antimitotic helicene, hel...
Autores principales: | Rushworth, James L., Thawani, Aditya R., Fajardo-Ruiz, Elena, Meiring, Joyce C. M., Heise, Constanze, White, Andrew J. P., Akhmanova, Anna, Brandt, Jochen R., Thorn-Seshold, Oliver, Fuchter, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709948/ https://www.ncbi.nlm.nih.gov/pubmed/36465552 http://dx.doi.org/10.1021/jacsau.2c00435 |
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