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Sorafenib inhibits interferon production by plasmacytoid dendritic cells in hepatocellular carcinoma
BACKGROUND: Sorafenib is a multi-kinase inhibitor that shows antitumor activity in advanced hepatocellular carcinoma. Sorafenib exerts a regulatory effect on immune cells, including T cells, natural killer cells and dendritic cells. Studies have shown that plasmacytoid dendritic cells (pDCs) are fun...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710007/ https://www.ncbi.nlm.nih.gov/pubmed/36451110 http://dx.doi.org/10.1186/s12885-022-10356-2 |