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Sorafenib inhibits interferon production by plasmacytoid dendritic cells in hepatocellular carcinoma

BACKGROUND: Sorafenib is a multi-kinase inhibitor that shows antitumor activity in advanced hepatocellular carcinoma. Sorafenib exerts a regulatory effect on immune cells, including T cells, natural killer cells and dendritic cells. Studies have shown that plasmacytoid dendritic cells (pDCs) are fun...

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Detalles Bibliográficos
Autores principales:	Zhang, Xinning, Xu, Yong, Zhao, Guodong, Liu, Rong, Yu, Haisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710007/ https://www.ncbi.nlm.nih.gov/pubmed/36451110 http://dx.doi.org/10.1186/s12885-022-10356-2

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