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Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity

BACKGROUND: Breast cancer is a major health burden for women, worldwide. Lifestyle-related risk factors, such as obesity and being overweight, have reached epidemic proportions and contributes to the development of breast cancer. Doxorubicin (DXR) is a chemotherapeutic drug commonly used to treat br...

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Detalles Bibliográficos
Autores principales: Sedeman, Megan, Christowitz, Claudia, de Jager, Louis, Engelbrecht, Anna-Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710042/
https://www.ncbi.nlm.nih.gov/pubmed/36451148
http://dx.doi.org/10.1186/s12885-022-10189-z