Cargando…
Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity
BACKGROUND: Breast cancer is a major health burden for women, worldwide. Lifestyle-related risk factors, such as obesity and being overweight, have reached epidemic proportions and contributes to the development of breast cancer. Doxorubicin (DXR) is a chemotherapeutic drug commonly used to treat br...
Autores principales: | Sedeman, Megan, Christowitz, Claudia, de Jager, Louis, Engelbrecht, Anna-Mart |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710042/ https://www.ncbi.nlm.nih.gov/pubmed/36451148 http://dx.doi.org/10.1186/s12885-022-10189-z |
Ejemplares similares
-
Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model
por: Christowitz, Claudia, et al.
Publicado: (2019) -
Decreased Efficacy of Doxorubicin Corresponds With Modifications in Lipid Metabolism Markers and Fatty Acid Profiles in Breast Tumors From Obese vs. Lean Mice
por: Mentoor, Ilze, et al.
Publicado: (2020) -
Circadian Rhythms and Breast Cancer: The Role of Per2 in Doxorubicin-Induced Cell Death
por: Mitchell, Megan I., et al.
Publicado: (2015) -
Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death
por: Thomas, Mark, et al.
Publicado: (2020) -
Disparate Impact of Butyroyloxymethyl Diethylphosphate (AN-7), a Histone Deacetylase Inhibitor, and Doxorubicin in Mice Bearing a Mammary Tumor
por: Tarasenko, Nataly, et al.
Publicado: (2012)