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An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients

Misfolded α-synuclein oligomers are closely implicated in the pathology of Parkinson's disease and related synucleinopathies. The elusive nature of these aberrant assemblies makes it challenging to develop quantitative methods to detect them and modify their behavior. Existing detection methods...

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Detalles Bibliográficos
Autores principales: Kulenkampff, Klara, Emin, Derya, Staats, Roxine, Zhang, Yu P., Sakhnini, Laila, Kouli, Antonina, Rimon, Oded, Lobanova, Evgeniia, Williams-Gray, Caroline H., Aprile, Francesco A., Sormanni, Pietro, Klenerman, David, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710209/
https://www.ncbi.nlm.nih.gov/pubmed/36544716
http://dx.doi.org/10.1039/d2sc00066k