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Alkynyl Prins carbocyclization cascades for the synthesis of linear-fused heterocyclic ring systems

We report a Brønsted acid-catalyzed carbocyclization cascade, featuring condensation of an alcohol/sulfonamide with an aldehyde followed by an intramolecular three-component coupling involving an alkyne, an oxocarbenium/iminium ion, and an arene. A formal cycloaddition is embedded in the cationic ca...

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Detalles Bibliográficos
Autores principales: Hernandez, Jackson J., Frontier, Alison J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710218/
https://www.ncbi.nlm.nih.gov/pubmed/36544720
http://dx.doi.org/10.1039/d2sc04750k