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What is the impact of targeted therapies given within phase I trials on the cognitive function of patients with advanced cancer: a mixed-methods exploratory study conducted in an early clinical trials unit

INTRODUCTION: Novel therapies such as small protein molecule inhibitors and immunotherapies are tested in early phase trials before moving to later phase trials and ultimately standard practice. A key aim of these clinical trials is to define a toxicity profile, however, the emphasis is often on saf...

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Detalles Bibliográficos
Autores principales: Stapleton, Sarah, Darlington, Anne-Sophie Emma, de Bono, J S, Wiseman, Theresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710342/
https://www.ncbi.nlm.nih.gov/pubmed/36442900
http://dx.doi.org/10.1136/bmjopen-2021-050590