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Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer’s disease

A regular sleep-wake cycle plays a positive function that preserves synaptic plasticity and brain activity from neuropathological injuries. The hypothalamic neuropeptide orexin-A (OX-A) is central in sleep-wake regulation and has been found to be over-expressed in the cerebrospinal fluid (CSF) of pa...

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Detalles Bibliográficos
Autores principales: Forte, Nicola, Fernández-Rilo, Alba Clara, Palomba, Letizia, Marfella, Brenda, Piscitelli, Fabiana, De Girolamo, Paolo, Di Costanzo, Alfonso, Di Marzo, Vincenzo, Cristino, Luigia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710385/
https://www.ncbi.nlm.nih.gov/pubmed/36466600
http://dx.doi.org/10.3389/fnagi.2022.1004002