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Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer’s disease
A regular sleep-wake cycle plays a positive function that preserves synaptic plasticity and brain activity from neuropathological injuries. The hypothalamic neuropeptide orexin-A (OX-A) is central in sleep-wake regulation and has been found to be over-expressed in the cerebrospinal fluid (CSF) of pa...
Autores principales: | Forte, Nicola, Fernández-Rilo, Alba Clara, Palomba, Letizia, Marfella, Brenda, Piscitelli, Fabiana, De Girolamo, Paolo, Di Costanzo, Alfonso, Di Marzo, Vincenzo, Cristino, Luigia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710385/ https://www.ncbi.nlm.nih.gov/pubmed/36466600 http://dx.doi.org/10.3389/fnagi.2022.1004002 |
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