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KYA1797K, a Novel Small Molecule Destabilizing β-Catenin, Is Superior to ICG-001 in Protecting against Kidney Aging

INTRODUCTION: Aged kidney is characterized by mitochondrial dysfunction, cellular senescence, and fibrogenesis. The activation of Wnt/β-catenin signaling plays an important role in the initiation of kidney aging. However, the inhibiting strategies have not been discovered in detail. Here, we compare...

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Detalles Bibliográficos
Autores principales: Zhu, Mingsheng, Ling, Xian, Zhou, Shan, Meng, Ping, Chen, Qiyan, Chen, Shuangqin, Shen, Kunyu, Xie, Chao, Kong, Yaozhong, Wang, Maosheng, Zhou, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710484/
https://www.ncbi.nlm.nih.gov/pubmed/36466073
http://dx.doi.org/10.1159/000526139