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metaLINCS: an R package for meta-level analysis of LINCS L1000 drug signatures using stratified connectivity mapping

SUMMARY: Accessing the collection of perturbed gene expression profiles, such as the LINCS L1000 connectivity map, is usually performed at the individual dataset level, followed by a summary performed by counting individual hits for each perturbagen. With the metaLINCS R package, we present an alter...

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Detalles Bibliográficos
Autores principales: Kwee, Ivo, Martinelli, Axel, Khayal, Layal Abo, Akhmedov, Murodzhon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710587/
https://www.ncbi.nlm.nih.gov/pubmed/36699415
http://dx.doi.org/10.1093/bioadv/vbac064