Cargando…

MODalyseR—a novel software for inference of disease module hub regulators identified a putative multiple sclerosis regulator supported by independent eQTL data

MOTIVATION: Network-based disease modules have proven to be a powerful concept for extracting knowledge about disease mechanisms, predicting for example disease risk factors and side effects of treatments. Plenty of tools exist for the purpose of module inference, but less effort has been put on sim...

Descripción completa

Detalles Bibliográficos
Autores principales: de Weerd, Hendrik A, Åkesson, Julia, Guala, Dimitri, Gustafsson, Mika, Lubovac-Pilav, Zelmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710626/
https://www.ncbi.nlm.nih.gov/pubmed/36699378
http://dx.doi.org/10.1093/bioadv/vbac006