How sticky are our proteins? Quantifying hydrophobicity of the human proteome

SUMMARY: Proteins tend to bury hydrophobic residues inside their core during the folding process to provide stability to the protein structure and to prevent aggregation. Nevertheless, proteins do expose some ‘sticky’ hydrophobic residues to the solvent. These residues can play an important function...

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Detalles Bibliográficos
Autores principales: van Gils, Juami Hermine Mariama, Gogishvili, Dea, van Eck, Jan, Bouwmeester, Robbin, van Dijk, Erik, Abeln, Sanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710682/
https://www.ncbi.nlm.nih.gov/pubmed/36699344
http://dx.doi.org/10.1093/bioadv/vbac002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710682/
https://www.ncbi.nlm.nih.gov/pubmed/36699344
http://dx.doi.org/10.1093/bioadv/vbac002

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