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How sticky are our proteins? Quantifying hydrophobicity of the human proteome
SUMMARY: Proteins tend to bury hydrophobic residues inside their core during the folding process to provide stability to the protein structure and to prevent aggregation. Nevertheless, proteins do expose some ‘sticky’ hydrophobic residues to the solvent. These residues can play an important function...
Autores principales: | van Gils, Juami Hermine Mariama, Gogishvili, Dea, van Eck, Jan, Bouwmeester, Robbin, van Dijk, Erik, Abeln, Sanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710682/ https://www.ncbi.nlm.nih.gov/pubmed/36699344 http://dx.doi.org/10.1093/bioadv/vbac002 |
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