LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data

SUMMARY: Fragmentation patterns of cell-free DNA reflect the chromatin structure of the cells from which these fragments are derived. Nucleosomes protect the DNA from fragmentation, resulting in decreased sequencing coverage in regions of open chromatin. LIQUORICE is a user-friendly software tool th...

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Detalles Bibliográficos
Autores principales: Peneder, Peter, Bock, Christoph, Tomazou, Eleni M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Application Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710688/
https://www.ncbi.nlm.nih.gov/pubmed/36699368
http://dx.doi.org/10.1093/bioadv/vbac017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710688/
https://www.ncbi.nlm.nih.gov/pubmed/36699368
http://dx.doi.org/10.1093/bioadv/vbac017

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