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LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data
SUMMARY: Fragmentation patterns of cell-free DNA reflect the chromatin structure of the cells from which these fragments are derived. Nucleosomes protect the DNA from fragmentation, resulting in decreased sequencing coverage in regions of open chromatin. LIQUORICE is a user-friendly software tool th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710688/ https://www.ncbi.nlm.nih.gov/pubmed/36699368 http://dx.doi.org/10.1093/bioadv/vbac017 |