TOSCA: an automated Tumor Only Somatic CAlling workflow for somatic mutation detection without matched normal samples

MOTIVATION: Accurate classification of somatic variants in a tumor sample is often accomplished by utilizing a paired normal tissue sample from the same patient to enable the separation of private germline mutations from somatic variants. However, a paired normal sample is not always available, maki...

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Detalles Bibliográficos
Autores principales: Del Corvo, Marcello, Mazzara, Saveria, Pileri, Stefano A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Application Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710689/
https://www.ncbi.nlm.nih.gov/pubmed/36699358
http://dx.doi.org/10.1093/bioadv/vbac070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710689/
https://www.ncbi.nlm.nih.gov/pubmed/36699358
http://dx.doi.org/10.1093/bioadv/vbac070

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