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More accurate estimation of cell composition in bulk expression through robust integration of single-cell information

MOTIVATION: The rapid single-cell transcriptomic technology developments have led to an increasing interest in cellular heterogeneity within cell populations. Although cell-type proportions can be obtained directly from single-cell RNA sequencing (scRNA-seq), it is costly and not feasible in every s...

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Detalles Bibliográficos
Autor principal: Karimnezhad, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710693/
https://www.ncbi.nlm.nih.gov/pubmed/36699374
http://dx.doi.org/10.1093/bioadv/vbac049