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Xuebijing injection inhibited neutrophil extracellular traps to reverse lung injury in sepsis mice via reducing Gasdermin D

The mortality of sepsis and septic shock remains high worldwide. Neutrophil extracellular traps (NETs) release is a major cause of organ failure and mortality in sepsis. Targeting Gasdermin D (GSDMD) can restrain NETs formation, which is promising for sepsis management. However, no medicine is ident...

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Detalles Bibliográficos
Autores principales: Shang, Ting, Zhang, Zhi-Sen, Wang, Xin-Tong, Chang, Jing, Zhou, Meng-En, Lyu, Ming, He, Shuang, Yang, Jian, Chang, Yan-Xu, Wang, Yuefei, Li, Ming-Chun, Gao, Xiumei, Zhu, Yan, Feng, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710739/
https://www.ncbi.nlm.nih.gov/pubmed/36467039
http://dx.doi.org/10.3389/fphar.2022.1054176