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Glucose-responsive microneedle patch for closed-loop dual-hormone delivery in mice and pigs
Insulin and glucagon secreted from the pancreas with dynamic balance play a vital role in regulating blood glucose levels. Although distinct glucose-responsive insulin delivery systems have been developed, the lack of a self-regulated glucagon release module limits their clinical applications due to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710866/ https://www.ncbi.nlm.nih.gov/pubmed/36449622 http://dx.doi.org/10.1126/sciadv.add3197 |