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Molecular architecture of the Chikungunya virus replication complex

To better understand how positive-strand (+) RNA viruses assemble membrane-associated replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected cells, we determined both the high-resolution structure of the core RNA replicase of chikungunya virus and the native RC...

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Detalles Bibliográficos
Autores principales: Tan, Yaw Bia, Chmielewski, David, Law, Michelle Cheok Yien, Zhang, Kuo, He, Yu, Chen, Muyuan, Jin, Jing, Luo, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710867/
https://www.ncbi.nlm.nih.gov/pubmed/36449616
http://dx.doi.org/10.1126/sciadv.add2536