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Structure of human phagocyte NADPH oxidase in the resting state

Phagocyte oxidase plays an essential role in the first line of host defense against pathogens. It oxidizes intracellular NADPH to reduce extracellular oxygen to produce superoxide anions that participate in pathogen killing. The resting phagocyte oxidase is a heterodimeric complex formed by two tran...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Song, Kangcheng, Wu, Jing-Xiang, Geng, Xiao-Peng, Zheng, Liming, Gao, Xiaoyin, Peng, Hailin, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711523/
https://www.ncbi.nlm.nih.gov/pubmed/36413210
http://dx.doi.org/10.7554/eLife.83743