Cargando…

Deep proteome profiling reveals signatures of age and sex differences in paw skin and sciatic nerve of naïve mice

The age and sex of studied animals profoundly impact experimental outcomes in biomedical research. However, most preclinical studies in mice use a wide-spanning age range from 4 to 20 weeks and do not assess male and female mice in parallel. This raises concerns regarding reproducibility and neglect...

Descripción completa

Detalles Bibliográficos
Autores principales: Xian, Feng, Sondermann, Julia Regina, Gomez Varela, David, Schmidt, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711526/
https://www.ncbi.nlm.nih.gov/pubmed/36448997
http://dx.doi.org/10.7554/eLife.81431