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Deep proteome profiling reveals signatures of age and sex differences in paw skin and sciatic nerve of naïve mice
The age and sex of studied animals profoundly impact experimental outcomes in biomedical research. However, most preclinical studies in mice use a wide-spanning age range from 4 to 20 weeks and do not assess male and female mice in parallel. This raises concerns regarding reproducibility and neglect...
Autores principales: | Xian, Feng, Sondermann, Julia Regina, Gomez Varela, David, Schmidt, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711526/ https://www.ncbi.nlm.nih.gov/pubmed/36448997 http://dx.doi.org/10.7554/eLife.81431 |
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