Unleashing a novel function of Endonuclease G in mitochondrial genome instability

Having its genome makes the mitochondrion a unique and semiautonomous organelle within cells. Mammalian mitochondrial DNA (mtDNA) is a double-stranded closed circular molecule of about 16 kb coding for 37 genes. Mutations, including deletions in the mitochondrial genome, can culminate in different h...

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Detalles Bibliográficos
Autores principales: Dahal, Sumedha, Siddiqua, Humaira, Sharma, Shivangi, Babu, Ravi K, Rathore, Diksha, Sharma, Sheetal, Raghavan, Sathees C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711528/
https://www.ncbi.nlm.nih.gov/pubmed/36394256
http://dx.doi.org/10.7554/eLife.69916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711528/
https://www.ncbi.nlm.nih.gov/pubmed/36394256
http://dx.doi.org/10.7554/eLife.69916

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